Pharmaceutical stability of colloidal saccharated iron oxide injection in normal saline

Intravenous Iron Therapy with Saccharated Iron Oxide

The immediate hematologic effects of intravenous saccharated iron oxide.

Intravenous iron: evaluation of the use of saccharated iron oxide in iron deficiency states in obstetrics and gynecology.

By Ro G. HOLLY, M.D. T lIE P[JHPOSE of tisis repoi-t is to) esaluiotte the usse of iuntn’avenously adminiistere! sac(’isaratedl irons oxi(le. Sesese toxic reactiouns from tue inntravenous adminnistn’ationn of irons have, henetofore, I)n’eo’lu(le(l its inse its tine usstral clinnio’tsl hanmolhnng of irons defno-ieno(’y states. Saco’inarated ison oxide, a colloidal suspeunsioun of ferric chloride...

Intranuclear Aggregates of Ferritin in Liver Cells of Mice Treated with Saccharated Iron Oxide

Several months following parenteral injections of saccharated iron oxide into DBA/2J mice, granules rich in iron were found in nuclei of scattered parenchymal liver cells as well as in the cytoplasm. As seen in the light microscope, the intranuclear granules were brown; most of them measured between 0.5 micro and 1 micro in cross-section. They gave positive Prussian blue tests, and were not sel...

Glomerular Lesions and the Nephrotic Syndrome in Rabbits given Saccharated Iron Oxide Intravenously

Intravascular precipitates, comprised at least in part of iron, formed regularly in rabbits given one or more injections of a saccharated iron oxide preparation intravenously, and these lodged in numerous capillaries throughout the body, particularly those of the lungs and kidneys. Large numbers of the brownish precipitates remained in the capillaries of the renal glomeruli during the first few...